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Vinpocetine, Ethyl Apovincaminate


Vinpocetine

Description
Vinpocetine is an alkaloid extracted from the Periwinkle plant, Vinca minor.
Vinpocetine is more technically referred to as "ethyl apovincaminate."

Mechanism of action
cerebral metabolic enhancer and a selective cerebral vasodilator
enhances oxygen and glucose uptake from blood by brain neurons
increases neuronal ATP bio-energy production

Contraindications
avoid high doses in pregnant women

Side effects
Stomach/ GI upset; dry mouth, rapid heart beat, low blood pressure, and rash/ hives are the main (rarely occurring) reported side effects.

Standard dose
5 mg 3x/day. Those with neurological impairment should take 10 mg three times a day for 30 days, then reduce the dose to 5 mg three times a day
Research has typically used 30 to 60 mg per day of vinpocetine. Taking vinpocetine with food appears to dramatically improve its absorption.

 

 

 

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