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PABA, Para-amino benzoic acid


PABA

Functions
PABA is an anti-fibrotic agent
hormone potentiator - helps maintain hormone levels

Biochemistry
PABA is one of the basic constituents of folic acid

Toxicity
high doses may cause a fever and rash

Drug Interactions
sulfonamides (Sulfasalazine) are PABA metabolites

Therapeutics

Dermatology
fibrosis, vitiligo, pemphigus vulgaris
scleroderma, dermatomyositis, Peryonies disease
Gynecology
hormone deficiency, infertility
Immune
autoimmune disease - 2 g tid
Rocky Mountain Spotted Fever - 20 g qd
GI
ulcerative colitis - sulfasalazine is structurally similar to paba

 

 

 

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