Although over 20 estrogens have been identified, traditionally, only three have been clinically valuable: estrone (E1), estradiol (E2), and estriol (E3).
The most potent estrogen secreted by the ovary is estradiol.
The natural ratio of estrogens is typically 3-10% estrone, 3-10% estradiol, and 80-93% estriol.
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