levels peak around the age of 25-30 and then drops by 85-90% by the age of 70
17,20 desmolase, essential for synthesis of DHEA, is functionally reduced with aging
the zona reticularis of the adrenal gland, where DHEA is made, atrophies with age
insulin both inhibits the synthesis of DHEA and accelerates the breakdown of DHEA.
high levels are anabolic, anti-glucocorticoid activity, balances cortisol
DHEA has been associated with
the ability to stay thin and to make muscle
avoiding death from breast cancer (for women)
avoiding death from cardiovascular disease (for men)
appears to help improve memory and stress resistance
improves one's sense of "well-being".
Men with prostate cancer and women with reproductive cancers should avoid DHEA.
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