Methionine forms S-adenosyl methionine, SAM
Methionine is a sulfur donor
breakdown of estrogens and degradation of histamine
synthesis of carnitine, choline, creatine, epinephrine, melatonin
synthesis of nucleic acids
maintains cartilage health
RDA - adults - 1.5 g, children - 22 mg/kg
tuna, cheddar cheese, salmon
Methionine deficiency is usually related to overall protein malnutrition
SAM synthesis needs B-12, folate and methionine
osteoarthritis, pain, fibromyalgia
rare, first signs are nausea and GI irritation
use caution in bipolar disorders as SAM may precipitate a manic phase
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