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Timolol maleate, Blocadren, Timolide, Timolol


Timolol maleate is a non-selective beta-adrenergic receptor blocker used to treat high blood pressure and prevent heart attacks, and occasionally to prevent migraine headaches.
In its ophthalmic form, it is used to treat open-angle and occasionally secondary glaucoma by reducing aqueous humour production through blockade of the beta receptors on the ciliary epithelium.




angina, glaucoma, hypertension, migraine prophylaxis, myocardial infarction prophylaxis, ocular hypertension, post-myocardial infarction, tremor,

Side Effects

The most serious possible side effects include cardiac arrhythmias and severe bronchospasms. Timolol can also lead to fainting, stroke, congestive heart failure, depression, confusion, and impotence.

alopecia, AV block, bronchospasm, diarrhea, elevated hepatic enzymes, exfoliative dermatitis, fatigue, hallucinations, heart failure, hypertriglyceridemia, hypoglycemia, hypotension, impotence, libido decrease, musculoskeletal pain, myalgia, nausea/vomiting, nightmares, ocular irritation, ocular pain, pruritus, sinus bradycardia, skin hyperpigmentation, xerosis,

Drug-Vitamin-Herb Interactions

Negative interactions:

Calcium may form unabsorbable complex with atenolol. Take at a different time of day.

Coleus forskohlii
Coleus forskohlii relaxes blood vessels. Combining Coleus with beta-blockers may have unpredicatable effects on blood pressure.

Positive interactions:

Beta-blockers reduce HDL. Chromium can offset the adverse effect.

Coenzyme Q10
Beta-blockers (especially propanolol) inhibit the actions of enzymes that contain CoQ10.




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