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Simvastatin, Zocor

Description

Simvastatin is a statin, which inhibits HMG-CoA reductase. It is used to control hypercholesterolemia (high cholesterol) and to prevent cardiovascular disease.

Simvastatin is a synthetic derivate of a fermentation product of Aspergillus terreus.

Action

statin, HMG-CoA reductase inhibitor

Indications

hypercholesterolemia, hyperlipoproteinemia, myocardial infarction prophylaxis,

Side Effects

constipation, diarrhea, dizziness, dyspepsia, elevated hepatic enzymes, flatulence, headache, heartburn, impotence, insomnia, myalgia, myositis, myasthenia, renal intratubular obstruction, rhabdomyolysis (fever, muscle aches or cramps, unusual tiredness or weakness), skin rash

Drug-Vitamin-Herb Interactions


Negative interactions:

Chaparral, Comfrey, Coltsfoot
Chaparral, Comfrey, and Coltsfoot may be toxic to the liver, which adds to side effect of statin drugs.

Grapefruit juice
Grapefruit juice impairs the breakdown of several drugs, including statins.

Niacin
High-doses of niacin combined with statin drugs could increase the risk of muscle damage and kidney injury.

Red Yeast Rice
Red Yeast Rice contains natural substances identical to statins.


Positive interactions:

Coenzyme Q10 and Vitamins A, D, E and K
Cholesterol is a precursor to CoQ10 and vitamins A, D, E and K. Statin drugs can reduce their production.

 

 

 

Fantastic new books!

Complementary and Alternative Medical Lab Testing is chock full of references for over 100 diseases.

Nutritional Genetics is also a referenced resource with sections on over 100 diseases.

Great Health Quotes has wonderful quotations about health, healing, disease, doctors, and medicine, and it's FREE.

A Brief Introduction to Naturopathy and Naturopathic Medicine describes the history and modalities. It's also FREE.

 


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