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Risedronate, Actonel


Risedronate is a biphosphate.


biphosphate, binds to hydroxyapetate


Risedronate is used to prevent and treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause (change of life). Risedronate is also used to prevent and treat osteoporosis in men and women who are taking glucocorticoids (corticosteroids; a type of medication that may cause osteoporosis). Risedronate is also used to treat Paget's disease of the bone (a condition in which the body replaces healthy bones with weak bones). Risedronate is in a class of medications called bisphosphonates. It works by preventing bone breakdown and increasing bone density (thickness) to make bones stronger and less likely to break.

Side Effects

Stop taking risedronate and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); difficulty or pain when swallowing; pain or burning under your ribs or in your back; or new or worsening heartburn. Ê
Other, less serious side effects may be more likely to occur. Continue to take risedronate and talk to your doctor if you experience abdominal discomfort; stomach upset, nausea, vomiting, or diarrhea; headache; or muscle or joint soreness or aches. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Drug-Vitamin-Herb Interactions

Negative interactions:

Some experts suggest that calcium should be taken separately from biphosphates.




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