| Ranitidine, Zantac
Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
H2 antagonist, decreases stomach acid
aspiration prophylaxis, duodenal ulcer, dyspepsia, esophagitis, gastric ulcer, gastroesophageal reflux disease (GERD), multiple endocrine adenoma syndrome, NSAID-induced ulcer prophylaxis, pyrosis (heartburn), stress gastritis prophylaxis, systemic mastocytosis, Zollinger-Ellison syndrome,
abdominal pain, agitation, alopecia, constipation, delirium, depression, diarrhea, dizziness, elevated hepatic enzymes, gynecomastia, hallucinations, headache, hepatitis, impotence, insomnia, jaundice, leukopenia, libido decrease, maculopapular rash, nausea/vomiting, pancreatitis, pancytopenia, paranoia, Stevens-Johnson syndrome, thrombocytopenia, toxic epidermal necrolysis,
Magnesium (often found in antacids) may reduce the absorption of H2 antagonists. Take at a different time of day.
Folate absorption is best in an acidic environment. H2 antagonists reduce stomach acid which can lower folate absorption.
Vitamin B12 absorption may be impaired by H2 antagonists, which reduce stomach acid.
Iron and Zinc
Iron and Zinc absorption is inhibited by reduced stomach acid levels.
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