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Propylthiouracil, PTU

Description

Propylthiouracil is a thiourea antithyroid agent. Propylthiouracil binds to thyroid peroxidase and thereby inhibits the conversion of iodide to iodine.

Action

thiourea antithyroid agent

Indications

Propylthiouracil is used to treat hyperthyroidism.

Side Effects

Propylthiouracil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

* skin rash
* itching
* abnormal hair loss
* upset stomach
* vomiting
* loss of taste
* abnormal sensations (tingling, prickling, burning, tightness, and pulling)
* swelling
* joint and muscle pain
* drowsiness
* dizziness
* decreased white blood cells
* decreased platelets

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

* sore throat
* fever
* headache
* chills
* unusual bleeding or bruising
* right-sided abdominal pain with decreased appetite
* yellowing of the skin or eyes
* skin eruptions


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