| Promethazine, Mepergan, Phenergan, Promethegan
Promethazine is a first-generation H1 receptor antagonist anti-histamine and antiemetic drug.
Promethazine is a phenothiazine antipsychotic, although it is no longer used for that purpose.
anti-histamine, phenothiazine antipsychotic
adynamic ileus, agranulocytosis, akathisia, aplastic anemia, blurred vision, cholestasis, constipation, contact dermatitis, corneal opacification, diaphoresis, dizziness, drowsiness, dystonia, ejaculation dysfunction, eosinophilia, galactorrhea, headache, hyperprolactinemia, hypertension, hyperthermia, hypotension, hypothermia, impotence, injection site reaction, insomnia, jaundice, leukocytosis, leukopenia, libido decrease, mastalgia, menstrual irregularity, mydriasis, neuroleptic malignant syndrome, orthostatic hypotension, pancytopenia, parkinsonism, photosensitivity, priapism, retinopathy, seizures, sinus tachycardia, skin hyperpigmentation, tardive dyskinesia, thrombocytopenia, urinary retention, visual impairment, weight gain, xerostomia,
Kava may block dopamine worsening movement disorder side effects, may cause excess sedation.
Phenylalanine may worssen the side effect of tardive dyskinesia associated with antipsychotic medications.
St JohnÕs Wort
St JohnÕs Wort accelerates breakdown of olanzapine (Zyprexa) and clozapine (Clozaril).
St JohnÕs Wort and Dong quai
St JohnÕs Wort and Dong quai can cause sensitivity to sun, adding to the side effects of antipsychotic agents.
Sedative herbs: Kava, Passionflower, Hops, Ashwagandha, Calendula, Catnip, LadyÕs Slipper, Lemon Balm, Sassafras, Skullcap, and Yerba mansa.
Sedative herbs may cause excess sedation when used with antipsychotic agents.
Phenothiazines may increase yohimbe toxicity.
Phenothiazines inhibit enzymes containing CoQ10.
Ginkgo may help reduce side effects and increase efficacy of antipsychotic medications.
Milk Thistle may protect the liver against toxicity caused by phenothiazide drugs.
Vitamin E may help treat and prevent tardive dyskenisia (a side effect of phenothiazide drugs).
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