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Penicillamine, Cuprimine, Depen

Description

Penicillamine is a chelator that binds to copper.

Action

binds to copper, used in WilsonÕs disease

Indications

WilsonÕs disease

Side Effects

abdominal pain, agranulocytosis, anorexia, aplastic anemia, arthralgia, bleeding, chills, cough, diarrhea, diplopia, dysgeusia, dyspnea, exfoliative dermatitis, fever, glomerulonephritis, hematuria, hemolysis, leukopenia, maculopapular rash, myasthenia, nausea/vomiting, nephrotic syndrome, optic neuritis, pancytopenia, peripheral neuropathy, proteinuria, pruritus, stomatitis, thrombocytopenia, tinnitus, urticaria, wheezing,

Drug-Vitamin-Herb Interactions


Negative interactions:

Copper
Those with WilsonÕs disease should avoid copper

Iron
Iron may interfere with absorption. Take at a different time of day.

Magnesium
Magnesium may reduce with absorption. Take at a different time of day.


Positive interactions:

Vitamin B6
Penacillamine can deplete vitamin B6.

 

 

 

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