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Nizatidine, Axid

Description

Axid (Nizatidine) is a histamine H2-receptor antagonist that inhibits stomach acid production.

Action

H2 antagonist, decreases stomach acid

Indications

Axid is indicated for up to 8 weeks for the treatment of active duodenal ulcer. In most patients, the ulcer will heal within 4 weeks.

Axid is indicated for maintenance therapy for duodenal ulcer patients, at a reduced dosage of 150 mg h.s. after healing of an active duodenal ulcer. The consequences of continuous therapy with Axid for longer than 1 year are not known.

Axid is indicated for up to 12 weeks for the treatment of endoscopically diagnosed esophagitis, including erosive and ulcerative esophagitis, and associated heartburn due to GERD.

Axid is indicated for up to 8 weeks for the treatment of active benign gastric ulcer. Before initiating therapy, care should be taken to exclude the possibility of malignant gastric ulceration.

Side Effects

agitation, delirium, depression, diaphoresis, diarrhea, dizziness, elevated hepatic enzymes, fever, hallucinations, headache, hepatitis, jaundice, nausea/vomiting, paranoia, pruritus, urticaria,

Drug-Vitamin-Herb Interactions


Negative interactions:

Magnesium
Magnesium (often found in antacids) may reduce the absorption of H2 antagonists. Take at a different time of day.


Positive interactions:

Folate
Folate absorption is best in an acidic environment. H2 antagonists reduce stomach acid which can lower folate absorption.

Vitamin B12
Vitamin B12 absorption may be impaired by H2 antagonists, which reduce stomach acid.

Iron and Zinc
Iron and Zinc absorption is inhibited by reduced stomach acid levels.

 

 

 

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