Natural Health Research

Naturopathic Medicine
Health Quizzes
Medroxyprogesterone, Provera, Depo-Provera, Depo


Depo-Provera is synthetic progesterone used primarily as a hormonal birth control method.

Depo-Provera causes the ovaries to stop releasing eggs. It also has a progestogenic effect of increasing cervical mucus viscosity, thereby inhibiting sperm penetration.

Most women using Depo Provera experience disruption of menstrual bleeding patterns, something which has been called "menstrual chaos."


synthetic progesterone


amenorrhea, chronic obstructive pulmonary disease (COPD), contraception, dysfunctional uterine bleeding, endometrial carcinoma, osteoporosis, Pickwickian syndrome, renal cell carcinoma, respiratory depression, sleep apnea,

Side Effects

Most women using Depo Provera experience disruption of menstrual bleeding patterns, something which has been called "menstrual chaos." Altered menstrual bleeding patterns include irregular or unpredictable bleeding or spotting, or rarely, heavy or continuous bleeding. After continuous use, fewer experience irregular bleeding and more experience amenorrhea. By month 12 amenorrhea was reported by 55% of women, and by month 24 amenorrhea was reported by 68%. Some women may prefer amenorrhea. (But it is not a guaranteed effect of Depo.)

amenorrhea, anorexia, anxiety, appetite stimulation, bleeding, breast tenderness, depression, diarrhea, dysmenorrhea, edema, elevated hepatic enzymes, fatigue, galactorrhea, hepatitis, hirsutism, impotence, pulmonary embolism, thromboembolism, weakness, weight gain, weight loss,

Drug-Vitamin-Herb Interactions




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