| Levodopa, Dopar, Larodopa
Levodopa is an intermediate in dopamine biosynthesis used in the management of Parkinson's disease.
Larodopa is indicated in the treatment of idiopathic Parkinson's disease (Paralysis Agitans), postencephalitic parkinsonism, symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication, and manganese intoxication. It is indicated in those elderly patients believed to develop parkinsonism in association with cerebral arteriosclerosis.
Choreiform or dystonic movements, anorexia, nausea/vomiting, xerostomia, dysphagia, dysgeusia, sialorrhea, ataxia, increased hand tremor, headache, dizziness, numbness, weakness, faintness, bruxism, confusion, insomnia, nightmares, hallucinations, delusions, agitation, anxiety, malaise, fatigue, euphoria, cardiac arrhythmias, orthostatic hypotension, elevated hepatic enzymes.,
The combination of 5-HTP and carbidopa may cause a scleroderma-like condition.
Branched Chain Amino Acids, BCAAs
Amino acids in dietary proteins decrease effectiveness of levodopa.
Iron interferes with absorption of carbodopa and levodopa. Take at separate times.
Kava may interfere with the action of dopamine.
Higher doses of Vitamin B6 can reduce the therapeutic effect of levodopa alone in ParkinsonÕs disease.
Levodopa may deplete SAMe.
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