Natural Health Research

Naturopathic Medicine
Health Quizzes
Ketoconazole, Nizoral


Ketoconazole is a synthetic anti-fungal drug used to prevent and treat skin and fungal infections, especially in immunocompromised patients such as those with AIDS.

Ketoconazole is sold commercially as the anti-dandruff shampoo, Nizoral.


azole antifungal, inhibits fungal cell wall synthesis


Actinomadura madurae, Actinomadura sp., Aspergillus flavus, Aspergillus fumigatus, Blastomyces dermatitidis, blastomycosis, Candida albicans, Candida parapsilosis, Candida tropicalis, candidiasis, candiduria, chromomycosis, Coccidioides immitis, coccidioidomycosis, Cryptococcus neoformans, cyclosporine therapy, Enterococcus sp., Epidermophyton floccosum, esophagitis, fungal keratitis, fungal prophylaxis, Histoplasma capsulatum, histoplasmosis, Leishmania braziliensis, Leishmania major, Leishmania mexicana, Leishmania panamensis, Leishmania tropica, leishmaniasis, Malassezia furfur, Microsporum audouinii, Microsporum canis, Microsporum gypseum, Nocardia sp., onychomycosis, oropharyngeal candidiasis (thrush), Paracoccidioides brasiliensis, paracoccidioidomycosis, Petriellidium boydii, Phialophora sp., prostate carcinoma, seborrheic dermatitis, Sporothrix schenckii, Staphylococcus aureus, Staphylococcus epidermidis, tinea capitis, tinea corporis, tinea cruris, tinea manuum, tinea pedis, tinea versicolor, Torulopsis glabrata, Trichophyton mentagrophytes, Trichophyton rubrum, Trichophyton tonsurans, vulvovaginal candidiasis,

Side Effects

dizziness, drowsiness, elevated hepatic enzymes, gynecomastia, hepatitis, impotence, libido decrease, nausea/vomiting, photophobia, pruritus,

Drug-Vitamin-Herb Interactions

Negative interactions:

Grapefruit juice
Grapefruit juice decreases absorption of itraconazole.




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