Natural Health Research

Naturopathic Medicine
Health Quizzes
Isotretinoin, Accutane


Isotretinoin is a vitamin A analog used to treat severe acne.


vitamin A analog


acne vulgaris

Side Effects

abdominal pain, alopecia, anemia, arthralgia, bleeding, blurred vision, cheilitis, conjunctivitis, corneal opacification, depression, diarrhea, diplopia, elevated hepatic enzymes, epistaxis, fatigue, headache, hepatitis, hypercholesterolemia, hyperostosis, hypertriglyceridemia, increased intracranial pressure, myalgia, nausea/vomiting, photophobia, photosensitivity, thrombocytopenia, xerosis, xerostomia,

Drug-Vitamin-Herb Interactions

Negative interactions:

St JohnÕs Wort and Dong Quai
St JohnÕs Wort and Dong Quai may increase sensitivity to sunlight adding to side effect of accutane.

Vitamin A
Do not combine Vitamin A with synthetic vitamin A as they may increase each otherÕs toxicity.




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