Natural Health Research

Naturopathic Medicine
Health Quizzes
Isosorbide dinitrate, ISDN, Isosorbide, Imdur, Isordil, Titradose


Isosorbide dinitrate is a nitrate used as a vasodilator.


nitrate, nitroglycerine



Side Effects

cyanosis, diaphoresis, flushing, headache, hypotension, methemoglobinemia, nausea/vomiting, orthostatic hypotension, palpitations, sinus tachycardia, syncope, tolerance, xerostomia,

Drug-Vitamin-Herb Interactions

Mixed interactions:

N-Acetyl Cysteine (NAC)
NAC might help nitroglycerine work better, but may cause severe headaches with nitroglycerine.

Positive interactions:

Vitamin C
Vitamin C may help reduce tolerance and keep nitroglcerine effective.




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