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Naturopathic Medicine
Health Quizzes
Insulin, Humulin


Insulin is a polypeptide hormone that regulates carbohydrate metabolism. Insulin is produced in the Islets of Langerhans in the pancreas.

Patients with type 1 diabetes mellitus (IDDM) have an absolute deficiency of the hormone and depend on exogenous insulin (commonly injected subcutaneously) for their survival.

Patients with type 2 diabetes mellitus (NIDM) have either relatively low insulin production or insulin resistance or both.




diabetes mellitus, diabetic ketoacidosis, hyperkalemia, nutritional supplementation,

Side Effects

hyperinsulism, hypoglycemia, hypokalemia, injection site reaction, insulin resistance, nausea/vomiting, pruritus, sinus tachycardia, Somogyi effect,

Drug-Vitamin-Herb Interactions

Negative interactions:

Ipriflavone may increase the effects of antidiabetics which may cause hypoglycemia.

Potassium citrate
Potassium citrate may decrease levels of sulfonylurea antidiabetic drugs.

St JohnÕs Wort and Dong quai
St JohnÕs Wort and Dong quai may cause sensitivity to the sun, adding to side effect of antidiabetics.

Mixed interactions:

Chromium improves blood sugar control, which may cause hypoglycemia with antidiabetic agents.

Ginseng lowers blood sugar levels, which may cause hypoglycemia with antidiabetic agents.

Diabetes may cause low levels of magnesium.

Magnesium increases the absorption of sulfonylurea antidiabetics.

Magnesium lowers blood sugar levels, which may cause hypoglycemia if used with antidiabetic agents.

Vanadium has an insulin-like action, which may cause hypoglycemia if used with antidiabetic agents.

Vitamin E
Antidiabetic supplements - Lipoic acid, Carnitine

Antibiabetic Herbs: Aloe, Bitter mellon, Bilberry, Burdock, Dandelion, Fenugreek, Garlic, Gymnema
Antibiabetic herbs may cause hypoglycemia if used with antidiabetic agents.

Antibiabetic Supplements: Lipoic acid, Carnitine
Antibiabetic supplements may cause hypoglycemia if used with antidiabetic agents.

Positive interactions:

Calcium corrects vitamin B12 malabsorption caused by metformin and phenformin.

Coenzyme Q10
Antidiabetic drugs interfere with the activity of enzymes containing CoQ10.

Vitamin B12
Metformin and phenformin cause malabsorption of vitamin B12.




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