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Fondaparinux, Arixtra

Description

Fondaparinux is a synthetic and specific inhibitor of activated Factor X (Xa).

Action

inhibits Factor X

Indications

ARIXTRA Injection is indicated for the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism:
¥ in patients undergoing hip fracture surgery, including extended prophylaxis;
¥ in patients undergoing hip replacement surgery;
¥ in patients undergoing knee replacement surgery;
¥ in patients undergoing abdominal surgery who are at risk for thromboembolic complications.
ARIXTRA Injection is indicated for:
¥ the treatment of acute deep vein thrombosis when administered in conjunction with warfarin sodium, and
¥ the treatment of acute pulmonary embolism when administered in conjunction with warfarin sodium when initial therapy is administered in the hospital.

Side Effects

Hemorrhage: During ARIXTRA administration, the most common adverse reactions were bleeding complications
Thrombocytopenia
Elevations of Serum Aminotransferases

Drug-Vitamin-Herb Interactions

 

 

 

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