Natural Health Research

Naturopathic Medicine
Health Quizzes
Ethacrynic acid, Edecrin


Ethacrynic acid is a loop diuretic


loop diuretic



Side Effects

agranulocytosis, anorexia, azotemia, confusion, diarrhea, dysphagia, fatigue, GI bleeding, headache, hearing loss, hyperglycemia, hyperuricemia, hypocalcemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, hypotension, hypovolemia, interstitial nephritis, malaise, nausea/vomiting, neutropenia, orthostatic hypotension, polyuria, thrombocytopenia, tinnitus,

Drug-Vitamin-Herb Interactions

Negative interactions:

Licorice contains glycyrrhizic acid, which promotes potassium loss in urine. Switch to DGL.

St JohnÕs Wort and Dong quai
St JohnÕs Wort and Dong Quai can cause sensitivity to sunlight, which may add to the side effects of loop diuretics.

Positive interactions:

Loop diuretics can deplete potassium.

Loop diuretics can deplete potassium.

Vitamin B1
Furosemide may deplete vitamin B1 (thiamin).




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