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Ethacrynic acid, Edecrin

Description

Ethacrynic acid is a loop diuretic

Action

loop diuretic

Indications

hypertension

Side Effects

agranulocytosis, anorexia, azotemia, confusion, diarrhea, dysphagia, fatigue, GI bleeding, headache, hearing loss, hyperglycemia, hyperuricemia, hypocalcemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, hypotension, hypovolemia, interstitial nephritis, malaise, nausea/vomiting, neutropenia, orthostatic hypotension, polyuria, thrombocytopenia, tinnitus,

Drug-Vitamin-Herb Interactions


Negative interactions:

Licorice
Licorice contains glycyrrhizic acid, which promotes potassium loss in urine. Switch to DGL.

St JohnÕs Wort and Dong quai
St JohnÕs Wort and Dong Quai can cause sensitivity to sunlight, which may add to the side effects of loop diuretics.


Positive interactions:

Magnesium
Loop diuretics can deplete potassium.

Potassium
Loop diuretics can deplete potassium.

Vitamin B1
Furosemide may deplete vitamin B1 (thiamin).

 

 

 

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