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Digoxin, Lanoxin

Description

Digoxin is a cardiac glycoside extracted from the foxglove plant, digitalis

Action

cardiac glycoside

Indications

atrial fibrillation, atrial flutter, heart failure, paroxysmal atrial tachycardia,

Side Effects

anorexia, atrial tachycardia, AV block, blurred vision, confusion, constipation, diarrhea, drowsiness, fatigue, gynecomastia, headache or migraine, hyperkalemia, hypokalemia, impotence, libido decrease, nausea/vomiting, photophobia, PR prolongation, premature ventricular contractions (PVCs), sinus bradycardia, ST-T wave changes, syncope, visual impairment, xanthopsia

Drug-Vitamin-Herb Interactions


Negative interactions:

Hawthorn
Hawthorn has similar effects on the heart.

Horsetail
Horsetail can deplete potassium (one animal study)

Licorice
Licorice contains glycyrrhizic acid which promotes potassium loss. This may increase digoxin toxicity

Siberian Ginseng
Siberian Ginseng may interfere with digoxin readings causing false high levels.

St JohnÕs Wort
St JohnÕs Wort decreases levels of digoxin.


Positive interactions:

Calcium
Digoxin may increase calcium loss causing depletion.

Magnesium
Low levels of magnesium can increase digoxin toxicity. Take at a different time.

 

 

 

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