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Clonidine, Catapres, Combipres

Description

Clonidine is an alpha-2 adrenergic antagonist

Action

antihypertensive, alpha-2 adrenergic antagonist

Indications

autism, cyclosporine nephrotoxicity prophylaxis, diabetic neuropathy, diarrhea, ethanol withdrawal, hot flashes, hypertension, hypertensive emergency, hypertensive urgency, menopausal symptoms, nicotine withdrawal, opiate agonist withdrawal, pheochromocytoma diagnosis, scleroderma renal crisis (SRC), Tourette's syndrome,

Side Effects

abdominal pain, constipation, contact dermatitis, dizziness, drowsiness, dysuria, ejaculation dysfunction, erythema, fatigue, headache, hypertension, impotence, libido decrease, orthostatic hypotension, palpitations, pruritus, sedation, sinus bradycardia, sinus tachycardia, skin hyperpigmentation, urinary retention, withdrawal, xerostomia,

Drug-Vitamin-Herb Interactions


Negative interactions:

Yohimbe
Yohimbe has an effect on blood pressure that may directly oppose that of Clonidine.


Positive interactions:

Coenzyme Q10
Several drugs that are used to lower blood pressure (especially propanolol) may inhibit the actions of enzymes containing CoQ10.

 

 

 

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