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Ciprofloxacin, Cipro

Description

Ciprofloxacin (Cipro) is an antibiotic, fluoroquinolone, inhibits DNA gyrase.

Action

antibiotic, inhibits DNA gyrase

Indications

Acinetobacter calcoaceticus, Aeromonas caviae, Aeromonas hydrophila, bone and joint infections, bronchiectasis, bronchitis, Brucella melitensis, brucellosis, Campylobacter coli, Campylobacter fetus, Campylobacter jejuni, cellulitis, chancroid, Chlamydia trachomatis, Citrobacter diversus, Citrobacter freundii, conjunctivitis, corneal ulcer, Corynebacterium sp., cystitis, diabetic foot ulcer, Edwardsiella tarda, Eikenella corrodens, endocarditis, Enterobacter aerogenes, Enterobacter agglomerans, Enterobacter cloacae, Enterococcus faecalis, epididymitis, Escherichia coli, Flavobacterium sp., Gardnerella vaginalis, gastroenteritis, gonorrhea, Haemophilus ducreyi, Haemophilus influenzae (º-lactamase negative), Haemophilus influenzae (º-lactamase positive), Haemophilus parainfluenzae, Hafnia alvei, Helicobacter pylori, infectious arthritis, infectious diarrhea, Klebsiella oxytoca, Klebsiella pneumoniae, Legionella bozemanii, Legionella dumoffii, Legionella gormanii, Legionella jordanis, Legionella longbeachae, Legionella micdadei, Legionella pneumophila, Legionella wadsworthii, Legionnaire's disease, Leptospira interrogans, Listeria monocytogenes, lower respiratory tract infections, lung abscess, Moraxella catarrhalis, Moraxella sp., Morganella morganii, Mycobacterium avium complex (MAC), Mycobacterium avium, Mycobacterium chelonae, Mycobacterium intracellulare, Mycobacterium fortuitum, Mycobacterium tuberculosis, Neisseria gonorrhoeae, Neisseria meningitidis, osteomyelitis, Pasteurella multocida, Plasmodium falciparum, pneumonia, prostatitis, Proteus mirabilis, Proteus vulgaris, Providencia rettgeri, Providencia stuartii, Pseudomonas aeruginosa, Rickettsia conorii, Salmonella enteritidis, Salmonella typhi, Serratia marcescens, Shigella flexneri, Shigella sonnei, shigellosis, skin and skin structure infections, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus saprophyticus, Streptococcus agalactiae (group B streptococci), Streptococcus bovis, Streptococcus dysgalactiae, Streptococcus pneumoniae, Streptococcus pyogenes (group A º-hemolytic streptococci), traveler's diarrhea, traveler's diarrhea prophylaxis, tuberculosis, typhoid fever, urinary tract infection (UTI), Vibrio cholerae, Vibrio parahaemolyticus, Vibrio vulnificus, Viridans streptococci, Yersinia enterocolitica,

Side Effects

angina, arthropathy, cardiac arrest, corneal deposits, diarrhea, headache, increased intracranial pressure, interstitial nephritis, myocardial infarction, nausea/vomiting, palpitations, photosensitivity, premature ventricular contractions (PVCs), pruritus, restlessness, seizures, tendon rupture,

Drug-Vitamin-Herb Interactions


Negative interactions:

Fennel
Fennel may reduce levels of ciprofloxacin, possibly impairing its effectiveness.

St JohnÕs Wort and Dong quai
St JohnÕs Wort and Dong quai increase sensitivity to sunlight, adding to the side effect of fluoroquinolones.

Calcium
Calcium may interfere with absorption. Take at a different time of day.

Iron
Iron may interfere with absorption. Take at a different time of day.

Zinc
Zinc may interfere with absorption. Take at a different time of day.


Positive interactions:

Lactobacillus acidophilus
Probiotics replace normal intestinal bacteria, which may reduce the side effect of diarrhea associated with antibiotics.

Sacchromyces boulardii
Sacchromyces boulardii may prevent antibiotic-related diarrhea.

Vitamin K
Antibiotics may cause vitamin K deficiency by destroying the beneficial bacteria that produce it.

 

 

 

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