Natural Health Research

Naturopathic Medicine
Health Quizzes
Bupropion, Wellbutrin, Zyban


Bupropion is an antidepressant of the aminoketone class. It is a selective catecholamine (norepinephrine and dopamine) reuptake inhibitor.


anti-depressant, inhibits dopamine reuptake


major depression

Side Effects

agitation, anorexia, anxiety, blurred vision, confusion, constipation, diaphoresis, dizziness, dysgeusia, hallucinations, headache, hypertension, insomnia, libido decrease, maculopapular rash, menstrual irregularity, nausea/vomiting, palpitations, paranoia, premature ventricular contractions (PVCs), pruritus, psychosis, restlessness, seizures, tremor, ventricular tachycardia, weight loss, xerostomia

Drug-Vitamin-Herb Interactions

Negative interactions:

Sedative herbs: Kava, Valerian, Passionflower, Hops
Sedative herbs may cause excess sedation when combined with antidepressants.

Tyrosine is a precursor to catecholamines (dopamine).




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