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Atenolol, Tenormin

Description

Atenolol is a beta-blocker. Atenolol was developed as a replacement for propanolol in the treatment of hypertension.
Propranolol is known to readily cross the blood-brain barrier (BBB) into the brain, causing side-effects such as depression and nightmares; atenolol was specifically developed to be unable to pass through the blood-brain barrier in order to prevent this effect.

Action

beta-blocker

Indications

acute myocardial infarction, angina, ethanol withdrawal, hypertension, migraine prophylaxis, myocardial infarction prophylaxis,

Side Effects

agranulocytosis, alopecia, AV block, depression, diarrhea, dizziness, dyspnea, exfoliative dermatitis, fatigue, heart failure, hyperglycemia, hypertriglyceridemia, hypoglycemia, hypotension, impotence, nausea/vomiting, pruritus, sinus bradycardia, skin hyperpigmentation, wheezing, xerosis,

Drug-Vitamin-Herb Interactions


Negative interactions:

Calcium
Calcium may form unabsorbable complex with atenolol. Take at a different time of day.

Coleus forskohlii
Coleus forskohlii relaxes blood vessels. Combining Coleus with beta-blockers may have unpredicatable effects on blood pressure.


Positive interactions:

Chromium
Beta-blockers reduce HDL. Chromium can offset the adverse effect.

Coenzyme Q10
Beta-blockers (especially propanolol) inhibit the actions of enzymes that contain CoQ10.

 

 

 

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