Natural Health Research

Naturopathic Medicine
Health Quizzes
Aspirin, Bayer, acetylsalicylic acid, ASA


Aspirin or acetylsalicylic acid (acetosal) is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory.

Aspirin also has and anticoagulant (Òblood-thinningÓ) effect and is used in long-term low-doses to prevent heart attacks.

Salicin was isolated from White willow (Salix alba) to its crystalline form in 1828 by Henri Leroux, a French pharmacist, and Raffaele Piria, an Italian chemist.


ASA, analgesic, anti-inflammatory, NSAID


acute myocardial infarction, arterial thromboembolism prophylaxis, colorectal carcinoma prophylaxis, coronary artery occlusion prophylaxis, fever, headache, juvenile rheumatoid arthritis (JRA), Kawasaki disease, migraine, mild pain, myocardial infarction prophylaxis, osteoarthritis, pericarditis, post-myocardial infarction, preeclampsia prophylaxis, prosthetic heart valves, transient ischemic attack (TIA), rheumatoid arthritis, stroke prophylaxis, unstable angina,

Side Effects

angioedema, bleeding, bronchospasm, dyspepsia, elevated hepatic enzymes, erythema nodosum, GI bleeding, hepatitis, interstitial nephritis, maculopapular rash, nausea/vomiting, purpura, Reye's syndrome, thrombocytopenia, tinnitus, urticaria,

Drug-Vitamin-Herb Interactions

Negative interactions:

Arginine stimulates gastrin production which increases stomach acid. This can irritate the stomach.

Feverfew has similar actions. Combining Feverfew with NSAIDs may increase the risk of side effects.

Natural blood thinners: Garlic, Ginkgo, Vitamin E, Policosanol, Dong quai, Ginger, Horse chestnut, Red clover, Fish oils, and OPCs.
Natural blood thinners may increase the tendency to bleed, a side effect of NSAIDs.

Potassium, magnesium, and calcium citrate
Citrates alkalinize the urine which decrease the therapeutic effect of NSAIDs and ASA.

St JohnÕs Wort and Dong quai
St JohnÕs Wort and Dong Quai can cause sensitivity to sunlight, which may add to side effects of NSAIDs.

Positive interactions:

Cayenne may help prevent gastric bleeding.

Colostrum may help protect against ulcers caused by NSAIDs.

Folate may be depleted by NSAIDs.

Licorice (DGL)
Licorice (DGL) may help protect the stomach against gastric damage caused by NSAIDs.

Vitamin C
Vitamin C may be depleted by NSAIDs.




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