Infertility is defined as failure to conceive after one year of unprotected intercourse.
Most couples have than one factor.
Endocrine dysfunction (e.g., hypothyroidism, hypogonadism, abnormal puberty, hyperprolactinemia, hypopituitarism) often associated with abnormalities of ovulation or spermatogenesis.
Sexual dysfunction (e.g., premature ejaculation) may contribute to the problem
Semen abnormalities can be caused by: Cimetidine, Spironolactone, Furadantin, Sulfasalazine, Marijuana, Chemotherapeutic agents, Cocaine, and Occupational or environmental hazards Infertiltity is associated with SLE, celiac disease.
Infertility may also be due to autoimmune disease (anti-sperm antibodies).
Current medical research focuses on the therapeutic action of prostaglandins in infertility.
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