Hypercholesterolemia is defined as serum cholesterol greater than 200 mg/dL (5.18 mmol/L). A high risk is 240 mg/dL (6.22 mmol/L) or more. The high density lipoprotein fraction of cholesterol (HDL) is considered protective, while the low density lipoprotein (LDL) is considered atherogenic. Prevalence increases with age.
Causes of primary hypercholesterolemia include: Diet; Heredity; Obesity; Sedentary life-style; Stress. Secondary: Hypothyroidism; Diabetes mellitus; Nephrotic syndrome; Obstructive liver disease; Progestins; Anabolic steroids; Diuretics except indapamide (Lozol); Beta blockers except those with intrinsic sympathomimetic activity (ISA); and some immunosuppressants.
Risk factors include obesity and heredity.
Standard labs can be used to identify the underlying causes,which include: Hypothyroidism and Diabetes mellitus.
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