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Cystic Fibrosis


Description

Cystic Fibrosis is a generalized, autosomal recessive disorder of infants, children and young adults with widespread dysfunction of the exocrine glands. Characteristics include chronic pulmonary disease, pancreatic insufficiency, abnormally high levels of electrolytes in the sweat and less frequently biliary cirrhosis and diabetes mellitus.

Cystic Fibrosis is the most common lethal genetic disease.

Causes

Autosomal recessive genetic defect



RISK FACTORS

Positive family history (rarely seen due to recessive nature)

Conventional Labs

Elevation of sodium and chloride concentrations in sweat (quantitative pilocarpine iontophoresis sweat test)

Genetic screening if sweat test inadequate

Stool trypsin and chymotrypsin absent or diminished

72 hour fecal fat excretion - increased fat in stool

Decreased albumin, fat soluble vitamins

CF gene screen (reference lab)

Pseudomonas in respiratory secretions

 

 

 

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A Brief Introduction to Naturopathy and Naturopathic Medicine describes the history and modalities. It's also FREE.

 


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