herb vitamin nutrition
NaturDoctor.com
Nutrition, Herbs, Vitamins
Classical Homeopathy
Ronald Steriti, ND, PhD
Licensed Naturopathic Physician
(239) 659-2684
Diseases
Vitamins
Library
Books
Store
Research
Natural Health
Forum
Health Quiz
About
Drugs
Links
My new web site NaturoBase.com has a lot more information - over 6,000 research studies, etc!

Visit the NaturDoctor Store for professional nutritional supplements.

Basic Nutritional Support
Hormone Panels
Children's Health.
Men's Health
Women's Health
Detoxification
Liver
Digestion Support
Heart and Cholesterol
Musculoskeletal



Finally, a Healthy Energy Drink for you and your kids!

Information on Chronic Myelagenous Leukemia


Description

Chronic myelagenous leukemia (CML) is also referred to as Chronic Myeloid, Chronic Myelocytic and Chronic Granulocytic Leukemia. CML is a clonal proliferation caused by malignant transformation of a pluripotent cell. The characteristic of CML is overproduction of granulocytes (neutrophils, eosinophils and basophils). Marrow invasion replaces all cells leading to increased red blood cell, platelet and white blood cell counts. The clinical course is slowly progressive. Median survival is approximately 40 months, when acute leukemia develops.

Symptoms of CML include fatigue, purpura, hives and pruritis due to histamine release. Signs include anemia, purpura, swollen gums (due to cellular infiltrate), splenomegaly, and “chloroma” (red-brown skin papules that become green when blood is squeezed out).

A blood smear will show moderately elevated white blood cells (mostly myelocytes), which may persist for years and be benign. Basophils are elevated and marrow mast cells are increased. Platelets are increased in number although their function is impaired. Serum B12 levels are markedly increased, and uric acid levels are elevated.

The goal of treatment is palliation, not cure. With chemotherapy, usually the patient may be kept asymptomatic for long periods by keeping the white blood cell count below 50,000/uL.



Causes

Chronic myelagenous leukemia may be caused by ionizing radiation or other chromosomal damage that opens oncogenes. Incidence of CML is increased in patients with Down syndrome (abnormal chromosome 21) and Philadelphia chromosome (translocation of an oncogene from chromosome 9 to chromosome 22).

The Philadelphia chromosome translocation leads to the formation of a new protein called bcr-abl, which acts as an oncogene to cause CML cells to develop and grow.

The cause of CML is unknown, but it has been linked to exposure to benzene and high doses of radiation.

Risk factors are thought to include some combination of viruses (e.g. Epstein-Barr virus-associated lymphoproliferative disorder, EBV-LPD), genetic and immunologic factors, and exposure to radiation and certain chemicals.

One specific enzyme, tyrosine kinase, is believed to cause more than 97 percent of all cases. Druker and researchers from Novartis Pharmaceuticals found a way to stop that enzyme six years ago and have been testing and refining it ever since with a compound called STI-571, also called Gleevec. Gleevec is a chemical inhibitor of the Bcr/Abl tyrosine kinase,

Myelotoxic agents (eg, ionizing radiation, benzene, alkylating agents)

Damage to the bone marrow by agents, such as benzene and ionizing radiation, may cause CML.

Conventional Labs



Specialty Lab Tests

Detoxification Profile, Standard
Adrenocortex Stress Profile


Products to consider

Detoxification Factors, 60 Caps
Anti-Oxidant 60c


Natural Therapies

Most natural health web sites put a list of herbs, vitamins and nutritional supplements along with citations from scientific studies.

Have you found this to be confusing, since there are so many to choose from?

A far simpler way is to choose a supplement from the appropriate body system, such as liver support, detoxification, etc.
A well formulated supplement works a lot better than separate vitamins and usually costs a lot less.
Please call me at (239) 659-2684 if you would like some assistance in choosing an appropriate product.

I can't diagnose or treat diseases by phone, but I can assist you in making better choices. I also can send some relevant articles to read. The first ten minutes are free (as long as you purchase from my web site).

What's your next step?

The next step, after you have been diagnosed with a disease, is to find out what is the specific cause, and then choose supplements that address it. Phone consults are my specialty. Please call my at (239) 659-2684 to schedule a consultation.

The choice is yours

I recommend that you make an informed choice, and the goal of this web site is to provide you with the information to make a wise choice when it comes to your health and wellness.

As you can see, I don't sell any vitamins on this web site. There are thousands of vitamin stores that will sell you whatever vitamin you want, and many of them offer discounts.

If you are interested in some high-quality basic nutritional supplements, I recommend visiting the Store You will find my recommendations for a multiple, tasty chewable fiber wafers, high-potency probiotics, and fish oils.

Good luck in your journey towards health and wellness!!

Why don't you tell me what vitamins to take for this disease?

Unfortunately, that would be a clear violation of FDA regulations. Also, one of the most important aspect of naturopathy is: "Treat the person, not the disease". This is a profound statement, and many people have spent thousands of dollars on vitamins listed in books or web sites for a specific disease. This is what I call "vending machine medicine". It rarely works! The solution is to find a naturopathic physician, such as myself, to assist you.


NaturDoctor.com

Ronald Steriti, ND, PhD
Natural Health Coach and Consultant
Call today (239) 659-2684

Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. If you have or suspect that you have a medical problem, promptly contact your health care provider. Information and statements on this site have not been evaluated by the Food and Drug Administration.

© 2002